Day two of Disrupt 2025 is here, and San Francisco’s Moscone West is buzzing with a full slate of speakers, hands-on workshops, curated networking, and plenty of evening meetups. If you haven’t secured your pass, on-site registration is still open, and mid-event pricing includes a 50% discount off the standard walk-up rate.
Plan your day and make the most of the conference energy:
– Expo Hall: Open 8 a.m.–5 p.m., the show floor features 300+ startups showcasing new products, demos, and deal-ready opportunities. It’s a prime spot to scout your next investment or partnership, so build time into your schedule to walk the floor and talk to founders.
– Women of Disrupt Breakfast: From 8–10 a.m. at the Deal Flow Cafe, this first-come, first-served reception invites anyone identifying as female to connect, learn, and network with peers across the startup and venture ecosystem.
– Networking all day: From 9 a.m.–5 p.m., use Braindate to join or host 1:1 and small-group sessions in the Networking Lounge. Investors and founders should also stop by the Deal Flow Cafe, an exclusive space designed for coffee-fueled conversations that can turn into term sheets. And don’t underestimate hallway serendipity—some of the best intros happen between sessions or in the Expo Hall.
Sessions designed to inform and inspire
Disrupt Stage highlights:
– No Filters: Vinod Khosla on the Future of Tech – Vinod Khosla (Founder, Khosla Ventures)
– The Startup Battlefield – Session 3 – Judges: Jon Chu (Khosla Ventures), Madison Faulkner (NEA), Ilya Kirnos (SignalFire), Miloni Madan Presler (Institutional Venture Partners), Rinki Sethi (Lockstep)
– What’s Next for Netflix and Streaming Itself – Elizabeth Stone (CTO, Netflix)
– From Mirror to What’s Next – Brynn Putnam (Founder, MIRROR; CEO, Board)
– Slate’s Auto Electric Truck – A first look with Chris Barman (CEO, Slate Auto)
– The Startup Battlefield – Session 4 – Judges: Leslie Feinzaig (Graham & Walker VC), Sara Ittelson (Accel), Doug Pepper (ICONIQ)
– Storming the Gates: Scaling Consumer AI – Phoebe Gates (Co-Founder, Phia), Sophia Kianni (Co-Founder, Phia)
AI Stage highlights:
– Betting on the Next Wave: What VCs Want in AI Startups – Steve Jang (Kindred Ventures), Aileen Lee (Cowboy Ventures), Jon McNeil (DVx Ventures)
– Creative Machines and Where AI Meets Imagination – Prateek Dixit (Pocket Entertainment), Soyoung Lee (TwelveLabs), Nikola Todorovic (Wonder Dynamics)
– AI Meets the Future of Work with Mercer’s Brendan Foody – Brendan Foody (CEO, Mercer)
– The Post-Training Revolution: How Reinforcement Learning Is Upending the AI Infra Stack – Eric Anderson (Scale Venture Partners), Kyle Corbitt (CoreWeave)
– Why the Next Frontier Is Search – Edo Liberty (Pinecone)
– From Web Pages to Autonomous Agents: Linking Today’s Web to Tomorrow’s Data Layer – Or Lenchner (Bright Data)
– Intelligence in Motion and the Future of Physical AI – Jeff Cardenas (Apptronik), Raquel Urtasun (Waabi)
– Can You Vibe Code Enterprise Software? – Arun Gupta (JetBrains), Mark Pollack (Spring OSS Contributor)
– Synthetic Voices and Real Impact – Mati Staniszewski (ElevenLabs)
– AI That Scales: Lessons From the Frontlines – Sanjay Dhawan (SymphonyAI), Tamara Pattison (The Save Mart Companies)
– Building Intelligence for Modern Defense – Ethan Thornton (Mach Industries)
– Driving Intelligence – Alex Kendall (Wayve)
Builders Stage highlights:
– How to Nail Product-Market Fit – Rajat Bhageria (Chef Robotics), Ann Bordetsky (NEA), Murali Joshi (ICONIQ)
– Designing Products for the AI Age – Andrew Reed (Sequoia Capital), Yuhki Yamashita (Figma), Zach Lloyd (Warp)
– How to Pitch When You’re at the Inception Stage – Wesley Chan (FPV Ventures), Charles Hudson (Precursor Ventures)
– Do Startups Still Need Silicon Valley? – Anh-Tho Chuong (Lago), David Hall (Revolution/Rise of the Rest), Tawni Nazario-Cranz (SignalFire)
– Building What’s Next with the Minds Behind Twitter and Meta – Adam Bain, Dick Costolo, David Fischer (01 Advisors)
– Where VCs Are Placing Their Bets in 2026 – Nina Achadjian (Index Ventures), Jerry Chen (Greylock), Peter Deng (Felicis)
Breakout Stage highlights:
– Agentic AI for Startups: Automate, Adapt, and Accelerate Growth – Anjali Mann (Microsoft), Anmol Rastogi (Amazon)
– Leading for Impact: Engineering at the Speed of AI – Andrew Berman (Runlayer), Dima Dzhulgakov (Fireworks AI), Suraj Patel (MongoDB), Eno Reyes (Factory)
– Rewriting Healthcare Workflows with AI – Zubair Ahsan (Max AI), Varun Krishnamurthy (Assured Health), Kanyi Maqubela (Kindred Ventures)
– Inside the Family Office Playbook: How the Wealthiest Invest in Startups and Venture Funds – Mariane Bekker (Founders Bay), Brett Horton (Paris-Roubaix Group), Daniel Idzkowski (I.D.I.T. Family Office)
– CVC: What’s Different? What’s Their Superpower? – Nicolas Sauvage (TDK Ventures)
– Startups, Stories, and the Fight for Attention – Jenna Birch (SISU), Allie Cefalo (Kleiner Perkins), Chantelle Darby (Darby PR)
– Embracing AI for a Better Digital Future – Meghana Dhar (Technology advisor and investor), Matt Madrigal (Pinterest)
Roundtables
These small-group, 30-minute discussions tackle practical, real-world challenges, including:
– The Future of Banking and Fintech: the AI Wave – Nnamdi Okike (645 Ventures)
More roundtables run throughout the day; check the event app or on-site program for times and locations.
Don’t miss these additional attractions
– StrictlyVC programming
– Pitch Showcase Stage
– Side events scattered around the city throughout the week
Tips to maximize your day
– Build a mixed agenda: Combine big-stage inspiration with hands-on breakouts and a few roundtables.
– Leave buffer time between sessions: That’s when the best chance meetings happen.
– Walk the Expo Hall strategically: Target startups by sector, then loop back for deeper dives.
– Investors and founders: Block time in the Deal Flow Cafe for focused conversations.
– Share your experience: Post photos, takeaways, and recommendations using the event’s official hashtag. Follow along on LinkedIn, Instagram, X, YouTube, Facebook, and TikTok for on-the-ground updates.
Key details
– Location: Moscone West, San Francisco
– Dates: October 27–29, 2025
– Registration: On-site ticketing remains open, with mid-event discounts available today
Whether you’re here to discover breakout startups, meet investors, recruit talent, or learn from industry leaders across AI, product, fintech, healthcare, and defense, day two delivers a packed agenda and countless opportunities to connect. Have fun out there and make it a day of deals, insights, and new relationships.San Francisco is buzzing as Disrupt 2025 takes over Moscone West, and the lineup is built to help founders, builders, and investors get ahead. From AI economics and agent safety to creator-led growth and energy independence, here’s your high-impact guide to what’s happening and why it matters.
What’s on the main stage
– Why founders need to be on camera: With social reach redefining brand power, Hanieh Sigari (EllieMD) and Uptin Saiidi (UP10 Media) break down how executives can win on video and build trust at scale.
– From tokens to turbines: Caleb Appleton (Bison Ventures) explains the new economics of AI—from compute constraints and model costs to the real-world infrastructure powering the next wave.
– Prototyping, tuning & scaling GenAI with open models: Aishwarya Srinivasan (Fireworks AI) shares pragmatic workflows for building fast, tuning smart, and scaling responsibly with open systems.
– The invisible AI revolution: Brad Cordova and Benjamin Kwon (Super.AI) spotlight the unseen AI automations quietly transforming operations and margins across industries.
– How smart brands win with creator-led videos: Peter Sleiman and Uptin Saiidi (UP10 Media) reveal playbooks for performance-driven storytelling that converts.
– How to train your model—taming AI agents without breaking them [encore]: Kyla Guru (Anthropic) covers safety guardrails, alignment, and reliability for agentic systems.
– The winning formula: turn your business into a trusted, scalable community: Tasneem Amina and Justine Palefsky (Kindred) share how community can be a growth engine, not just a channel.
– From inception to enterprise: selling AI agents that scale: Allison Baum Gates (SemperVirens Venture Capital) maps how buyers evaluate agents, what wins pilots, and what drives expansion.
– Powering the future home: energy independence starts here: Jenny Zhang (EcoFlow) explores resilient home energy systems and what’s next for consumer power technology.
– Encores you asked for: A repeat of Aishwarya Srinivasan’s session on open-model GenAI scaling, plus a replay of the Kindred community masterclass with Justine Palefsky and Tasneem Amina.
For investors: LP and GP perspectives that matter
– Global high-tech at a crossroads: Dror Bin (Israel Innovation Authority) examines deep-tech’s role amid geopolitical shifts and new innovation hubs.
– The LP lens—liquidity, selection, and the future of ventures: Lara Banks (Makena Capital), Kelli Fontaine and Michael Kim (Cendana Capital), Adam Grosher (The J. Paul Getty Trust), and Matt Hodan (Lexington Partners) discuss pacing, secondaries, and where returns will concentrate next.
– GP perspectives on LP relationships: Kevin Hartz (A*) shares what strengthens GP–LP partnerships through cycles.
Note: This LP session returns by popular demand and is open to Investor Pass holders only.
Side events across San Francisco
The energy doesn’t stop at Moscone West. Company-hosted gatherings span panels, parties, and meetups across the city—ideal for founders, operators, and investors to connect. RSVP early to secure a spot.
Last call to join Disrupt 2025
There are two days left to plug into the conversations shaping startups, AI, investing, and the creator economy. Join thousands of founders, investors, and technologists in San Francisco—and take advantage of limited-time 50% off passes.
